SARS-CoV-2 variants have a high tendency and long-term transmission

Researchers analyzed data on three different types of anxiety and found that the viral load was high and the infection lasted longer than in B.1.1.7. All were more contagious than the real species, and transmission was also dependent on the census.

Acute acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has changed since it first appeared in late 2019. Several mutations of the virus have been observed, and some strains appear to be more contagious than the first, which also appears to avoid the immune system found in previous infections.

Some of these strains have been labeled as disturbing variants (VOCs) due to their high transmission and infection. This was also associated with the second and third waves of infection in many countries, leading to their close detection, either in the sequence of a complete virus genome or a reverse-transcription polymerase chain reaction (RT-PCR).

Other RT-PCR studies have suggested that VOCs may create higher viral load, but such studies are performed simultaneously. In a new study published on the medRxiv * preprint server, French researchers reported how different mutations affect viral kinetics in infection.

Viral load testing
Investigators used data from RT-PCR tests specifically for variables made between February and April 2021 in SARS-CoV-2 positive samples. They used data from more than 17,000 samples. About 73% of the samples belonged to the B.1.1.7 variant, 6% to the B.1.351 or P.1 variant, and the rest were wild.

A model was developed that included several interrelated factors, such as the patient’s age, genealogy of the virus, and whether the patient was hospitalized.

They found that the loads of the virus were different between a wild-type virus and a different variety. With the severity of B.1.1.7, the high viral load increased with age. The cycle values ​​of species B.1.351 and P.1 were slightly lower than those of the wild species, indicating relatively low viral loads of these species.

In addition, the rate of weight loss during HIV was less than the pressure of B.1.1.7 compared to wild-type viruses. The data also show very high loads and low levels of anemia in people in the hospital, about 1.5 days more.

Variants more infectious

There has been a strong correlation between the frequency of the cycle and the decrease in viral load, which promotes an equitable relationship between the rate of cycle and infection. These researchers found that there was a higher risk of transmitting the virus than wild-type viruses.

With the difficulty of B.1.1.7, large transfers were most prevalent in older countries such as Japan (profit between 41%) and France. In contrast, the variants of B.1.351 and P.1 were most evident in low-income countries such as Niger (average profit of 26%).

Therefore, the analysis shows that SARS-CoV-2 variants have a higher risk of transmission, depending on the population. The authors suggest that future studies should look at combining data cycle data and serological data to understand how the differences between B.1.351 and P.1 escape our body’s response.

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